Back to Search
Start Over
MR microscopy of water diffusion tensor in biological systems.
- Source :
- Applied Magnetic Resonance; Dec1998, Vol. 15 Issue 3/4, p333-341, 9p
- Publication Year :
- 1998
-
Abstract
- Diffusion tensor imaging (DTI) of the control and mechanically injured spinal cord of a rat in vitro and in vivo are reported. In vitro experiments were done on a home-built 6.4 T magnetic resonance microscope. Results for formaline-fixed samples show significant differences in diffusion tensor components between gray matter and white matter of the control spinal cord. Moreover, it is shown that already 6–10 min after the injury DTI can detect changes in water diffusion in areas extending far beyond the region of primary tissue damage. In vivo experiments were performed using a 9.4 T Magnex magnet and Bruker Medspec imaging system. Good-quality DTI images, free from motion artifacts were obtained. Results from control samples confirm differences in water diffusion between white matter and gray matter, observed in vitro. In vivo experiments show that characteristic changes in water diffusion observed in vitro 6–10 min after injury are preserved 60–360 min after injury, without significant alteration during this time. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09379347
- Volume :
- 15
- Issue :
- 3/4
- Database :
- Complementary Index
- Journal :
- Applied Magnetic Resonance
- Publication Type :
- Academic Journal
- Accession number :
- 49512774
- Full Text :
- https://doi.org/10.1007/BF03162019