Natural killer T cells: Picturing activation in action.

The article focuses on two separate studies which had visualized invariant natural killer T (iNKT) cells being activated in vivo. Both of these studies suggested a significant role for specialized tissue-resident macrophage populations in iNKT cell activation. One study tracked the behaviour of fluorescently labelled iNKT cells in lymph node. However, the second study visualized the behaviour of iNKT cells in the liver.