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Deregulated expression of TCL1 causes T cell leukemia in mice.

Authors :
Virgilio, Laura
Lazzeri, Cristina
Bichi, Roberta
Nibu, Ken-Ichi
Narducci, Maria Grazia
Russo, Giandomenico
Rothstein, Jay L.
Croce, Carlo M.
Source :
Proceedings of the National Academy of Sciences of the United States of America; 03/31/98, Vol. 95 Issue 7, p3885, 5p, 7 Color Photographs, 4 Diagrams, 2 Charts, 1 Graph
Publication Year :
1998

Abstract

Focuses on a study of the TCL1 oncogene on human chromosome 14q32.1, which is involved in the development of T cell leukemia in humans. Methodology used; Implication of the development of mature T cell leukemia in overexpression of the TCL1 gene in humans; Results and discussion.

Subjects

Subjects :
T cells
ONCOGENES

Details

Language :
English
ISSN :
00278424
Volume :
95
Issue :
7
Database :
Complementary Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
486034
Full Text :
https://doi.org/10.1073/pnas.95.7.3885