FHIT gene therapy prevents tumor development in Fhit-deficient mice.

Authors :: Dumon, Kristoffel R.
Ishii, Hideshi
Fong, Louise Y.Y.
Zanesi, Nicola
Fidanza, Vincenzo
Mancini, Rita
Vecchione, Andrea
Baffa, Raffaele
Trapasso, Francesco
During, Matthew J.
Huebner, Kay
Croce, Carlo M.
Source :: Proceedings of the National Academy of Sciences of the United States of America; 03/13/2001, Vol. 98 Issue 6, p3346, 6p, 20 Diagrams, 2 Charts
Publication Year :: 2001
Abstract: Clarifies the role of tumor suppressor gene FHIT in cancer development. Ability to inhibit tumor development by oral gene transfer; Potential of FHIT gene therapy as a novel clinical approach not only for treatment of early stages of cancer but also in prevention of human cancer.

Language :: English
ISSN :: 00278424
Volume :: 98
Issue :: 6
Database :: Complementary Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 4857252
Full Text :: https://doi.org/10.1073/pnas.061020098