Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity.

Authors :: Flores-Villanueva, Pedro O.
Yunis, Edmond J.
Delgado, Julio C.
Vittinghoff, Eric
Buchbinder, Susan
Leung, Jessica Y.
Uglialoro, Adele M.
Clavijo, Olga P.
Rosenberg, Eric S.
Kalams, Spyros A.
Braun, James D.
Boswell, Stephen L.
Walker, Bruce D.
Goldfeld, Anne E.
Source :: Proceedings of the National Academy of Sciences of the United States of America; 04/24/2001, Vol. 98 Issue 9, p5140, 6p, 3 Charts, 1 Graph
Publication Year :: 2001
Abstract: Identifies HLA-B antigens associated with the lack of HIV progression to AIDS. Division of HLA-B alleles into two mutually exclusive groups based on the expression of the molecular epitopes; Role in presenting viral peptides for immune recognition; Motif functions as a ligand for a natural killer cell inhibitory receptor.

Language :: English
ISSN :: 00278424
Volume :: 98
Issue :: 9
Database :: Complementary Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 4852591
Full Text :: https://doi.org/10.1073/pnas.071548198

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