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Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity.
- Source :
- Proceedings of the National Academy of Sciences of the United States of America; 04/24/2001, Vol. 98 Issue 9, p5140, 6p, 3 Charts, 1 Graph
- Publication Year :
- 2001
-
Abstract
- Identifies HLA-B antigens associated with the lack of HIV progression to AIDS. Division of HLA-B alleles into two mutually exclusive groups based on the expression of the molecular epitopes; Role in presenting viral peptides for immune recognition; Motif functions as a ligand for a natural killer cell inhibitory receptor.
Details
- Language :
- English
- ISSN :
- 00278424
- Volume :
- 98
- Issue :
- 9
- Database :
- Complementary Index
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America
- Publication Type :
- Academic Journal
- Accession number :
- 4852591
- Full Text :
- https://doi.org/10.1073/pnas.071548198