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Risks of Lynch Syndrome Cancers for MSH6 Mutation Carriers.
- Source :
- JNCI: Journal of the National Cancer Institute; Feb2010, Vol. 102 Issue 3, p193-201, 9p, 5 Charts, 1 Graph
- Publication Year :
- 2010
-
Abstract
- Background: Germline mutations in MSH6 account for 10%–20% of Lynch syndrome colorectal cancers caused by hereditary DNA mismatch repair gene mutations. Because there have been only a few studies of mutation carriers, their cancer risks are uncertain. [ABSTRACT FROM PUBLISHER]
- Subjects :
- CANCER risk factors
COLON cancer
GENETIC mutation
GENETIC disorders
DNA repair
GENES
Subjects
Details
- Language :
- English
- ISSN :
- 00278874
- Volume :
- 102
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- JNCI: Journal of the National Cancer Institute
- Publication Type :
- Academic Journal
- Accession number :
- 47988924
- Full Text :
- https://doi.org/10.1093/jnci/djp473