Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive...

Authors :: Renxue Wang
Salem, Myriam
Yousef, Ibrahim M.
Tuchweber, Beatriz
Ping Lam
Childs, Sarah J.
Helgason, Cheryl D.
Ackerley, Cameron
Phillips, M. James
Ling, Victor
Source :: Proceedings of the National Academy of Sciences of the United States of America; 02/13/2001, Vol. 98 Issue 4, p2011, 6p, 3 Black and White Photographs, 1 Diagram, 1 Chart, 5 Graphs
Publication Year :: 2001
Abstract: Reports that targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis. Inactivation of the spgp gene in mice; Analysis of spgp[sup -/-] mice; Secretion of bile acids; Tetra-hydroxylated bile acids; Lipid composition of bile in spgp[sup -/-] mice.

Language :: English
ISSN :: 00278424
Volume :: 98
Issue :: 4
Database :: Complementary Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 4700923
Full Text :: https://doi.org/10.1073/pnas.98.4.2011

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