Bone Mass Decreases in Morbidly Obese Women after Long Limb-Biliopancreatic Diversion and Marked Weight Loss Without Secondary Hyperparathyroidism. A Physiological Adaptation to Weight Loss?

The article discusses a study on the effect of marked weight loss after long limb-biliopancreatic diversion (BPD-LL) on bone mass and serum calcium, 25-OH-vitamin D and parathyroid hormone (PTH) levels in relation to calcium supplementation. The study involved two groups of healthy, morbidly obese, premenopausal women who underwent BPD-LL. A year after the surgery, both groups had similar body weight loss. The study concluded that marked weight loss after BPD-LL results in increased bone turnover without the appearance of secondary hyperparathyroidism.