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Effects of ketoconazole on ovulatory changes in the rat: implications on the role of a meiosis-activating sterol.

Authors :
Tsafriri, A
Tsafriri, Alex
Popliker, M
Popliker, Malka
Nahum, R
Nahum, Ravit
Beyth, Y
Beyth, Yoram
Source :
Molecular Human Reproduction; May98, Vol. 4 Issue 5
Publication Year :
1998

Abstract

Examines whether meiosis-activating sterols (MAS) play a physiological role in the resumption of meiosis in the rat when using ketoconazole as an inhibitor of sterol synthesis. Inhibition of ovulation; Ketoconazole-treated ovaries; Maturation and degeneration of oocytes; Luteinizing hormone-stimulated oocyte maturation; Follicular progesterone production.

Details

Language :
English
ISSN :
13609947
Volume :
4
Issue :
5
Database :
Complementary Index
Journal :
Molecular Human Reproduction
Publication Type :
Academic Journal
Accession number :
4508857
Full Text :
https://doi.org/10.1093/molehr/4.5.483