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Inhibition of oxytocin receptor function by direct binding of progesterone.

Authors :
Grazzini, Eric
Guillon, Gilles
Mouillac, Bernard
Zingg, Hans H.
Source :
Nature; 4/2/1998, Vol. 392 Issue 6675, p509, 4p, 3 Charts, 13 Graphs
Publication Year :
1998

Abstract

Presents research which studied the effect of progesterone on uterine sensitivity to oxytocin. Functions of the steroid hormone progesterone in mammals; Non-genomic action of progesterone on the uterine oxytocin receptor (OTR); Progesterone inhibiting oxytocin binding; Effects highly steroid- and receptor-specific; Direct interaction between a steroid hormone and a G-protein-coupled receptor; More.

Details

Language :
English
ISSN :
00280836
Volume :
392
Issue :
6675
Database :
Complementary Index
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
448078
Full Text :
https://doi.org/10.1038/33176