An L1 element intronic insertion in the black-eyed white (MITF[sup mi-bw]) gene: the loss of a single Mitf isoform responsible for the pigmentary defect and inner ear deafness.

Examines the DNA L1 element intronic insertion in the black-eyed white gene responsible for pigmentary defects and inner ear deafness. Role of microphthalmia-associated transcription factors in the development of pigment cells; Disruption of the neural-crest-derived melanocyte development.