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Single nucleotide polymorphism in the low-density lipoprotein receptor is associated with a threefold risk of stroke.
- Source :
- European Heart Journal; Jun2004, Vol. 25 Issue 11, p943-951, 9p
- Publication Year :
- 2004
-
Abstract
- Background More than 600 different, but rare, mutations in the low-density lipoprotein (LDL) receptor have been identified as the cause of familial hypercholesterolaemia. In contrast, only a single common amino acid-changing polymorphism (A370T) has been reported in this gene. The association of this polymorphism with variations in lipid levels is at present unclear. [ABSTRACT FROM PUBLISHER]
Details
- Language :
- English
- ISSN :
- 0195668X
- Volume :
- 25
- Issue :
- 11
- Database :
- Complementary Index
- Journal :
- European Heart Journal
- Publication Type :
- Academic Journal
- Accession number :
- 44420581