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PARP1 is required for adhesion molecule expression in atherogenesis.
- Source :
- Cardiovascular Research; Apr2008, Vol. 78 Issue 1, p158-166, 9p, 5 Graphs
- Publication Year :
- 2008
-
Abstract
- Aims: Atherosclerosis is the leading cause of death in Western societies and a chronic inflammatory disease. However, the key mediators linking recruitment of inflammatory cells to atherogenesis remain poorly defined. Poly(ADP-ribose) polymerase 1 (PARP1) is a nuclear enzyme, which plays a role in acute inflammatory diseases. [ABSTRACT FROM PUBLISHER]
Details
- Language :
- English
- ISSN :
- 00086363
- Volume :
- 78
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Cardiovascular Research
- Publication Type :
- Academic Journal
- Accession number :
- 44398967
- Full Text :
- https://doi.org/10.1093/cvr/cvm110