Deficiency of tumour necrosis factor-α and interferon-γ in bone marrow cells synergistically inhibits neointimal formation following vascular injury.

Aims: Neointimal formation after percutaneous coronary intervention (PCI), termed restenosis, limits therapeutic revascularization. Since it is now known that vascular injury involves an inflammatory response, we examined the role of tumour necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) in the neointimal formation after injury. [ABSTRACT FROM PUBLISHER]