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Inferring progression models for CGH data.
- Source :
- Bioinformatics; Sep2009, Vol. 25 Issue 17, p2208-2215, 8p, 2 Diagrams, 1 Chart, 1 Graph
- Publication Year :
- 2009
-
Abstract
- Motivation: One of the mutational processes that has been monitored genome-wide is the occurrence of regional DNA copy number alterations (CNAs), which may lead to deletion or over-expression of tumor suppressors or oncogenes, respectively. Understanding the relationship between CNAs and different cancer types is a fundamental problem in cancer studies. [ABSTRACT FROM PUBLISHER]
- Subjects :
- COMPARATIVE genomic hybridization
DNA
TUMOR suppressor genes
ONCOGENES
CANCER
Subjects
Details
- Language :
- English
- ISSN :
- 13674803
- Volume :
- 25
- Issue :
- 17
- Database :
- Complementary Index
- Journal :
- Bioinformatics
- Publication Type :
- Academic Journal
- Accession number :
- 44355810
- Full Text :
- https://doi.org/10.1093/bioinformatics/btp365