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Inferring progression models for CGH data.

Authors :
Liu, Jun
Bandyopadhyay, Nirmalya
Ranka, Sanjay
Baudis, M.
Kahveci, Tamer
Source :
Bioinformatics; Sep2009, Vol. 25 Issue 17, p2208-2215, 8p, 2 Diagrams, 1 Chart, 1 Graph
Publication Year :
2009

Abstract

Motivation: One of the mutational processes that has been monitored genome-wide is the occurrence of regional DNA copy number alterations (CNAs), which may lead to deletion or over-expression of tumor suppressors or oncogenes, respectively. Understanding the relationship between CNAs and different cancer types is a fundamental problem in cancer studies. [ABSTRACT FROM PUBLISHER]

Details

Language :
English
ISSN :
13674803
Volume :
25
Issue :
17
Database :
Complementary Index
Journal :
Bioinformatics
Publication Type :
Academic Journal
Accession number :
44355810
Full Text :
https://doi.org/10.1093/bioinformatics/btp365