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Treatment Outcomes of Dental Flossing in Twins: Molecular Analysis of the Interproximal Microflora.

Authors :
Corby, Patricia M. A.
Biesbrock, Aaron
Bartizek, Robert
Corby, Andrea L.
Monteverde, Robin
Ceschin, Rafael
Bretz, Walter A.
Source :
Journal of Periodontology; Aug2008, Vol. 79 Issue 8, p1426-1433, 8p
Publication Year :
2008

Abstract

Background: The purpose of this study was to assess the effects of dental flossing on the microbial composition of interproximal plaque samples in matched twins. Methods: The study was a two-treatment, examiner-masked, randomized, parallel-group, controlled study. Fifty-one twin pairs between 12 and 21 years of age were randomized to a 2-week supervised and unsupervised treatment regimen consisting of tongue brushing and toothbrushing or tongue brushing and toothbrushing plus flossing. The reversecapture checkerboard hybridization assay was used to assess levels (abundance) of 26 microbial species in interproximal plaque samples collected from six sites per subject. An integrative computational predictive model estimated average changes in microbial abundance patterns of selected bacterial species from baseline to 2 weeks by comparing treatment groups. Results: After the 2-week study period, putative periodontal pathogens and cariogenic bacteria were overabundant in the group that did not floss compared to the group that performed flossing. Those included Treponema denticola, Porphyromonas gingivalis, Tannerella torsythia (previously T. forsythensis), Prevotella intermedia, Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinomycetemcomitans), and Streptococcus mutans. Microbial species that are not consistent with the development of periodontal disease or dental caries were overabundant in the group that did floss compared to the non-flossing group. Conclusion: In a well-matched twin cohort, tooth and tongue brushing plus flossing significantly decreased the abundance of microbial species associated with periodontal disease and dental caries after a 2-week program. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00223492
Volume :
79
Issue :
8
Database :
Complementary Index
Journal :
Journal of Periodontology
Publication Type :
Academic Journal
Accession number :
44298828
Full Text :
https://doi.org/10.1902/jop.2008.070585