Untitled.

Source :: Diabetes; Jun2009 Supplement 1, Vol. 58 Issue S1, pA1-A646, 646p, 5 Black and White Photographs, 3 Diagrams, 354 Charts, 182 Graphs
Publication Year :: 2009
Abstract: The article summarizes research on insulin secretion regulation. They include secretion in isolated cultured islets from short-chain 3-hydroxyacyl-isobutyryl-coenzyme A (CoA)-dehydrogenase (SCHAD) knockout mice to examine the mechanism of insulin dysregulation in SCHAD deficiency, potential of mammalian target of rapamycin (mTOR) inhibition as therapy for intractable hypoglycemia caused by malignant insulin secretion, and the effect of mTOR complex 1 (mTORC1) activation on mitochondrial function in pancreatic β cells.