Sulfur-Bonded Coordination Compounds of Palladium(II) and Platinum(II) and Their Antimicrobial Activity.

The synthetic, spectroscopic, and biological studies of some new palladium(II) and platinum(II) complexes derived from biologically active sulfur donor ligands 1H-indol-2,3-dione benzothiazoline (Bzt1H) and 5-nitro-1H-indol-2,3-dione benzothiazoline (Bzt2H) have been described. The reactions were carried out in 1:2 molar ratios. The authenticity of the benzothiazolines and their complexes has been established on the basis of elemental analyses; molecular weight determinations; and IR, 1H NMR, 13C NMR, and UV spectral studies. Based on IR and 1H NMR spectral studies, a square-planar structure has been assigned to these complexes. Studies were conducted to assess the comparative growth inhibiting potential of the synthesized complexes against the benzothiazolines for a variety of fungal and bacterial strains. The studies demonstrate that the ligands and complexes possess antimicrobial properties. Further, it was noted that the growth-inhibiting potential of the complexes is greater than the parent benzothiazolines. [ABSTRACT FROM AUTHOR]