Redundant function of retinoic acid receptor isoforms in leukemogenesis unravels a prominent function of genome topology and architecture in the selection of mutagenic events in cancer.

Authors :: Marinelli, A.
Bossi, D.
Pelicci, P. G.
Minucci, S.
Source :: Leukemia (08876924); Feb2009, Vol. 23 Issue 2, p417-419, 3p, 2 Graphs
Publication Year :: 2009
Abstract: A letter to the editor is presented about the role of retinoic acid receptor isoforms in leukemogenesis which also shows a significant function of genome topology as well as in the selection of mutagenic events in cancer.

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