Perspective Knockdown resistance to DDT and pyrethroids: from target-site mutations to molecular modelling.

The article reports on the target-site resistance of insects to pyrethroids and DDT. It mentions that insecticides target the sodium channel proteins of nerve-cell membranes and paralyzes insects which result in death. In some insects the sodium channel protein are evolved and respond differently to insecticides by preventing binding. The study explores the research on the processes in sodium channel protein response to insecticides to contribute to the improvement of future products. An overview of the study is provided.