Effect of Molecular Weight and End Capping on Poly(lactic-co-glycolic acid) Ultrasound Contrast Agents.

The article discusses contrast agents (CA) used in the ultrasound medical imaging modality, examining the effects of end capping and molecular weight on hollow CA's which are formed in the double emulsion process. A CA with 50:50 poly (lactic-co-glycolic-acid) (PLGA) is used in a double emulsion process, the authors state. Other topics include non-end capped PLGA which provides a maximum molecular weight enhancement of 18.5 dB and CA's tailored to particular applications by varying the choice of polymer.