New Results on Energy Balance Analysis of Metabolic Networks.

Authors :: Hutchison, David
Kanade, Takeo
Kittler, Josef
Kleinberg, Jon M.
Mattern, Friedemann
Mitchell, John C.
Naor, Moni
Nierstrasz, Oscar
Pandu Rangan, C.
Steffen, Bernhard
Sudan, Madhu
Terzopoulos, Demetri
Tygar, Doug
Vardi, Moshe Y.
Weikum, Gerhard
Ghosh, Ashish
De, Rajat K.
Zhou, Qinghua
Shiu, Simon C. K.
Pal, Sankar K.
Source :: Pattern Recognition & Machine Intelligence (978-3-540-77045-9); 2007, p433-438, 6p
Publication Year :: 2007
Abstract: A central and long-standing objective of cellular physiology has been to understand the metabolic capabilities of living cells. In this paper, we perform optimization of metabolic networks in E.Coli under both flux and energy balance constraints. The impact of the energy balance is investigated on the behavior of metabolic networks. Different from the existing work, the preliminary results showed that the impact of imposing energy balance constraints on the biological metabolic systems is very limited. [ABSTRACT FROM AUTHOR]