Acute ST-Segment Elevation Myocardial Infarction: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

The article focuses on various treatments for acute ST-segment elevation (STE) myocardial infarction (MI) including fibrinolytic, antiplatelet and antithrombin treatment. Suggestions for remedy of STE MI patients were also discussed. It is noted that STE MI is induced by the disruption of the coronary plaque with exposure of substances that promote platelet activation, adhesion and aggregation, and thrombin generation leading to an occluded epicardial infarct-related artery (IRA).