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Antigen Load and Viral Sequence Diversification Determine the Functional Profile of HIV-1Specific CD8 T Cells.
- Source :
- PLoS Medicine; May2008, Vol. 5 Issue 5, pe100, 1p, 3 Charts, 4 Graphs
- Publication Year :
- 2008
-
Abstract
- Marcus Altfeld and colleagues suggest that the exhaustion of virus-specific CD8+ T cells during chronic HIV infection likely results from the persistence of antigen. [ABSTRACT FROM AUTHOR]
- Subjects :
- T cells
HIV infections
HIV
VIRAL load
LYMPHOCYTES
ANTIGENS
Subjects
Details
- Language :
- English
- ISSN :
- 15491277
- Volume :
- 5
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- PLoS Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 32427491
- Full Text :
- https://doi.org/10.1371/journal.pmed.0050100