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Protein scaffold of a designed metalloenzyme enhances the chemoselectivity in sulfoxidation of thioanisole.

Authors :
Jun-Long Zhang
Dewain K. Garner
Lei Liang
Qian Chen
Yi Lu
Source :
Chemical Communications; Mar2008, Vol. 2008 Issue 14, p1665-1667, 3p
Publication Year :
2008

Abstract

We demonstrate that incorporation of MnSalen into a protein scaffold enhances the chemoselectivity in sulfoxidation of thioanisole and find that both the polarity and hydrogen bonding of the protein scaffold play an important role in tuning the chemoselectivity. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
2008
Issue :
14
Database :
Complementary Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
32120302
Full Text :
https://doi.org/10.1039/b718915j