PREVALENCE OF DYSLIPIDEMIAS IN PATIENTS WITH CHRONIC KIDNEY DISEASE FROM TRIBAL AREAS OF CHHATTISGARH PRESENTING TO A TERTIARY CARE HOSPITAL.

Aim: To evaluate the prevalence of dyslipidemia in chronic kidney disease patients (not on dialysis) from Tribal areas of Chhattisgarh. Materials and Methods: All Chronic Kidney Disease patients from tribal areas of Chhattisgarh admitted in Nephrology Unit, Department of Medicine, Pt.J.N.M.Medical College and B.R.A.M.Hospital Raipur (C.G.) during the year 2007 were studied. All patients were subjected to Fasting Lipid Profile analysis. Patients already on lipid lowering therapy or with thyroid or liver diseases were excluded from the study. Results: 61 patients were studied of which 57% were males and 43% females. Serum Total Cholesterol (>200 mg/dl) was found in 56.6% while 43.4% had S.Cholesterol (<200 mg/dl). (P value 0.05) 14.82%patients had HDL level <35 mg/dl, while 85.18% had HDL >35 mg/dl. Serum Triglyceride level >150 mg/dl was found in 54.25% patients (P=0.02). LDL level > 100 mg/dl was found in 61.39% (P=0.05). In diabetic patients, the mean total cholesterol level was 184.29 and mean LDL 105.2 mg/dl. In non diabetics, the mean total cholesterol level was 105.2 and mean LDL 97.10 mg/dl. (P= 0.05) The mean cholesterol level was 192.39 mg/dl in patients with glomerular disease and 164.13 mg/dl in patients with non glomerular disease (P=0.02). The LDL level was 107.0 mg/dl in patients with glomerular disease and 96.82 mg/dl in patients with non glomerular disease (P=0.05). Conclusion: Increased LDL level was the most common lipid abnormality encountered in the study (61%). Increased Triglycerides level was found in 54.25% patients and the p value (0.02) was found to be statistically significant. Increased Total Cholesterol level was found in 56.6% patients. Decreased HDL was found in 14.82%. Mean cholesterol and LDL levels were significantly different in diabetics and non diabetics (184.29 vs 169.32 mg/dl) and (105.2 vs 97.10 mg/dl) Mean cholesterol and LDL levels were higher among patients with glomerular disease versus non glomerular disease and the p value (0.02) was found to be statistically significant. [ABSTRACT FROM AUTHOR]