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Schönlein-Henoch purpura during pregnancy with successful outcome for mother and newborn.
- Source :
- BMC Dermatology; 2002, Vol. 2, p1-5, 5p, 4 Color Photographs
- Publication Year :
- 2002
-
Abstract
- Background: Schönlein-Henoch purpura is a systemic vasculitis that affects vessels of a small caliber and rarely reported in the literature. Case presentation: We report on a 35-year-old woman who developed palpable purpura with necrotizing cutaneous lesions on the lower limbs at 27 weeks of gestation. She also complained of epigastric pain and arthralgias. Histologic examination of a skin biopsy showed leukocytoclastic vasculitis with intravascular fibrin thrombi. The direct immunofluorescence analysis evidenced vascular deposits of IgA and C3 in the upper and mid-dermis. These findings were consistent with Schönlein-Henoch purpura. There was no evidence of renal involvement or placental dysfunction. The patient was treated with low-dose oral corticosteroids and a healthy infant was delivered by cesarean section. Examination of the placenta and the navel string disclosed no signs of vasculitis or infarction. Conclusions: Schönlein-Henoch purpura is rarely reported in pregnancy. Treatment with orally administred corticosteroids may lead to a beneficial outcome for mother and newborn. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14715945
- Volume :
- 2
- Database :
- Complementary Index
- Journal :
- BMC Dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 29322730
- Full Text :
- https://doi.org/10.1186/1471-5945-2-1