Can Biochemical Markers Serve as Surrogates for Imaging in Knee Osteoarthritis?

Authors :: Davis, C. R.
Karl, J.
Granell, R.
Kirwan, J. R.
Fasham, J.
Johansen, J.
Garnero, P.
Sharif, M.
Source :: Arthritis & Rheumatism; Dec2007, Vol. 56 Issue 12, p4038-4047, 10p, 5 Charts, 1 Graph
Publication Year :: 2007
Abstract: The article presents a study which determined the association between individual biochemical markers and radiographic features. Serum and urinary biochemical markers were assessed in patients with predominantly tibiofemoral knee osteoarthritis (OA). Results of principal components analysis suggest that biochemical marker combinations may be more sensitive than individual marker for reflecting structural damage in patients with knee OA.