Current Cell-based Approaches for the Treatment of Diabetes Mellitus.

The article describes the potential cell-based approaches for the treatment of diabetes mellitus. It discusses the role of the surrounding mesenchyme in providing most of the regulatory factors for the proper pancreatic development. An overview of the differentiation of embryonic stem cells into pancreatic ß-like-cells is offered. It is stated that the discovery of multipotent stem cells in adult tissue has resulted in a widespread belief in the possible effectiveness of cell therapy.