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S-Adenosylmethionine as a Biomarker for the Early Detection of Lung Cancer.

Authors :
Greenberg, Alissa K.
Rimal, Binaya
Felner, Kevin
Zafar, Subooha
Hung, Jerry
Eylers, Ellen
Phalan, Rendan
Meng Zhang
Goldberg, Judith D.
Crawford, Bernard
Rom, William N.
Naidich, David
Merali, Salim
Source :
CHEST; Oct2007, Vol. 132 Issue 4, p1247-1252, 6p, 4 Charts, 2 Graphs
Publication Year :
2007

Abstract

The article discusses the study of S-Adenosylmethionine (AdoMet) as a biomaker for the early detection of lung cancer. Accordingly, AdoMet is a major methyl donor for transmethylation reactions and propylamine donor for the biosynthesis of polyamines in biological systems. The study uses a high-performance liquid chromatography to analyze plasma AdoMet levels in triplicate samples from 68 patients.

Details

Language :
English
ISSN :
00123692
Volume :
132
Issue :
4
Database :
Complementary Index
Journal :
CHEST
Publication Type :
Academic Journal
Accession number :
27373698
Full Text :
https://doi.org/10.1378/chest.07-0622