Novel Reporter Gene Expression Systems for Monitoring Activation of the Aspergillus nidulans HOG Pathway.

The article discusses a study which presents novel reporter systems for monitoring activation of the Aspergillus nidulans high-osmolarity glycerol response (AnHOG) pathway. It is stated that AnHOG pathway involved in osmoadaptation. The study found that fludioxonil causes improper activation of HogA mitogen-activated protein kinase in A. nidulans. The results indicate that the reporter activity is regulated via HogA activation.