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The Role of β-Glucuronidase in Induction of Apoptosis by Genistein Combined Polysaccharide (GCP) in Xenogeneic Mice Bearing Human Mammary Cancer Cells.

Authors :
YUAN, LAN
WAGATSUMA, CHIHIRO
SUN, BUXIANG
KIM, JUNG‐HWAN
SURH, YOUNG‐JOON
Source :
Annals of the New York Academy of Sciences; 2004, Vol. 1010 Issue 1, p347-349, 3p
Publication Year :
2004

Abstract

In order to reveal the mechanisms underlying genistein combined polysaccharide (GCP) inhibition of tumor proliferation, we investigated the effects of GCP on the growth of human breast cancer cells transplanted to athymic nude mice. We further investigated the metabolism of genistein and its association with the β-glucuronidase activity in tumor and normal tissues. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00778923
Volume :
1010
Issue :
1
Database :
Complementary Index
Journal :
Annals of the New York Academy of Sciences
Publication Type :
Academic Journal
Accession number :
26277535
Full Text :
https://doi.org/10.1196/annals.1299.063