Sex and schizophrenia: vive la différence.

The article examines the issue of sex difference in schizophrenia. It discusses sex difference with regard to the age at onset of the disease, the course and outcome of schizophrenia, premorbid abnormalities of intellectual and social functioning in schizophrenia, disease incidence, differences in the non-nuclear symptoms of schizophrenia, familial risk, and normal brain morphology. As sex differences in schizophrenia become better documented, their significance to the comprehension of the disorder itself will become clearer.