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Value of the DST for Predicting Response of Patients With Major Depression to Hospitalization and Desipramine.
- Source :
- American Journal of Psychiatry; Nov90, Vol. 147 Issue 11, p1488-1492, 5p
- Publication Year :
- 1990
-
Abstract
- The authors examined the value of the dexamethasone suppression test (DST) for predicting response of patients with unipolar, non psychotic major depression to 1 week of hospitalization without antidepressant drugs and to a 4-week trial of desipramine at a fixed plasma level. The rates of response to hospitalization without drug treatment (defined as a score of 12 or less on the Hamilton Rating Scale for Depression) were not significantly different for the patients with a positive DST and those with a negative DST. This finding differs from those of prior studies of the DST and response to placebo. The responses of the DST-positive and DST-negative patients to desipramine also did not differ, a finding that replicates those in some prior reports. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0002953X
- Volume :
- 147
- Issue :
- 11
- Database :
- Complementary Index
- Journal :
- American Journal of Psychiatry
- Publication Type :
- Academic Journal
- Accession number :
- 24295309
- Full Text :
- https://doi.org/10.1176/ajp.147.11.1488