A new germacranolide-type sesquiterpene lactone from Tanacetum santolinoides.

A new germacranolide-type sesquiterpene lactone, 1α-hydroxy-3-oxo-7α,11βH-germacra-4Z,9Z-dien-12,6α-olide (1), was isolated from the CH2Cl2--MeOH extract of the aerial parts of Tanacetum santolinoides. Its structure was determined by spectroscopic techniques including, IR, high-resolution-EIMS, and extensive 400 MHz one- and two-dimensional NMR-analysis (1H, 13C-NMR, DEPT, 1H--1H COSY, HMQC, HMBC, and NOE experiments). [ABSTRACT FROM AUTHOR]