Microsatellites MCMA53 and MCMA16 on OAR15 are associated with susceptibility to atypical scrapie.

Authors :: Lühken, G.
Zieleniewicz, D.
Brandt, H. R.
Buschmann, A.
Groschup, M. H.
Erhardt, G.
Source :: Animal Genetics; Feb2007, Vol. 38 Issue 1, p88-89, 2p, 1 Chart
Publication Year :: 2007
Abstract: The article examines the microsatellites MCMA16, MCMA53, BMS2812, RM004 and MCM159 on sheep chromosome 15 (0AR15). It focuses on the association of their alleles with susceptibility to a typical animal disease. Scrapie-associated fibril immunoblotting and immunohistochemistry were employed to determine the type of scrapie. Results showed significant differences between atypical scrapie-positive sheep and flock mates. Further study on repeated data about population stratification is recommended.

Subjects :: SHEEP diseases
MICROSATELLITE repeats
IMMUNOHISTOCHEMISTRY
GENETICS
LIVESTOCK

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