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Finding the final pieces of the vitamin B12 biosynthetic jigsaw.

Authors :
Warren, Martin J.
Source :
Proceedings of the National Academy of Sciences of the United States of America; 3/28/2006, Vol. 103 Issue 13, p4799-4800, 2p, 1 Diagram
Publication Year :
2006

Abstract

The article comments on a study by G.R.O. Campbell and colleagues about an enzyme that appears to play a key role in the transformation of flavin in dimethylbenzimidazole (DMB). According to the author, the team proved that a mutant in bluB gene was able to grow in the presence of either vitamin B<subscript>12</subscript> or DMB but not in the presence of cobinamide. He also mentions the limitations of Campell's study.

Details

Language :
English
ISSN :
00278424
Volume :
103
Issue :
13
Database :
Complementary Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
20629785
Full Text :
https://doi.org/10.1073/pnas.0601030103