Long-Term Remission in Progressive Multifocal Leukoencephalopathy Caused by Idiopathic CD4+ T Lymphocytopenia: A Case Report.

Progressive multifocal leukoencephalopathy is caused by JC virus, an opportunistic infection of the central nervous system. Antiretroviral treatment for progressive multifocal leukoencephalopathy in human immunodeficiency virus-infected patients is beneficial, but few data exist for patients who are not infected with human immunodeficiency virus. Idiopathic CD4⁺ T lymphocytopenia excludes human immunodeficiency virus infection. We describe a patient with progressive multifocal leukoencephalopathy with underlying idiopathic CD4⁺ T lymphocytopenia in whom functional recovery occurred without antiviral therapy. [ABSTRACT FROM AUTHOR]