Back to Search Start Over

The Genetics of Human Cancer.

Authors :
Croce, Carlo M.
Koprowski, Hilary
Source :
Scientific American; Feb78, Vol. 238 Issue 2, p117-125, 9p, 9 Diagrams
Publication Year :
1978

Abstract

The article focuses on the genetics of human cancer. German zoologist Theodor Boveri formulated the somatic mutation hypothesis of the origin of cancer. According to Boveri's theory, the promordial cell of a malignant growth is a somatic cell that contains an abnormal process of a definite and wrongly combined chromosome complex. He recognized the importance of environmental factors such as chemical carcinogens and ionizing radiation as triggering agents in malignant transformation.

Details

Language :
English
ISSN :
00368733
Volume :
238
Issue :
2
Database :
Complementary Index
Journal :
Scientific American
Publication Type :
Periodical
Accession number :
19868174
Full Text :
https://doi.org/10.1038/scientificamerican0278-117