Evidence of cellular nicotinic receptor desensitization in rats exhibiting nicotine-induced acute tolerance.

The article discusses research on the evidence of cellular nicotinic receptor desensitization in rats, exhibiting nicotine-induced acute tolerance. It examines the relationship between in vivo pharmacological desensitization and brain regional nicotinic cholinergic receptors function. It provides information on the methods and materials used in the study. It also discusses the results of the study.