c-Flip expression and function in fetal mouse gonocytes.

Authors :: Giampietri, Claudia
Petrungaro, Simonetta
Klinger, Francesca G.
Coluccia, Pierpaolo
Paone, Alessio
Vivarelli, Elisabetta
Filippini, Antonio
De Cesaris, Paola
De Felici, Massimo
Ziparo, Elio
Source :: FASEB Journal; Jan2006, Vol. 20 Issue 1, p124-126, 3p, 1 Color Photograph, 1 Diagram
Publication Year :: 2006
Abstract: The article discusses c-Flip expression and function in fetal mouse genocytes. c-Flip is expressed in fetal male mouse gonads and its expression is developmentally regulated. Fas-dependent apoptosis in fetal testes is dependent on c-Flip levels. Initiator caspase-10 is expressed in fetal male mouse gonad and its activity is developmentally regulated.