Depression Update.

The article presents news briefs about clinical developments related to psychiatry. The Apaf-1 gene related to major depression is discovered by researchers working at Myriad Genetics Inc. This gene makes the (Apaf-1) protein, which is an activator of a cascade of events leading to the destruction of a cell. A study about the investigational drug SEP-225289, which is used for the treatment of major depressive disorder, has been initiated by Sepracor Inc. This drug has the potential to be a leading drug candidate in the newly emerging field of triple reuptake inhibitors.