Rapid maxillary expansion treatment could produce long-term transverse skeletal changes.

Data sources Medline, Medline In-Process and other Medline nonindexed citations, LILACS, Pubmed, Embase, Web of Science and the Cochrane Library were searched. Search terms were rapid palatal expansion or rapid maxillary expansion (RME), bone and bones or skeletal changes. Reference lists from retrieved articles were also examined.Study selection For inclusion, an article had to satisfy the following criteria: describe controlled clinical trials; make measurements for facial radiographs (anteroposterior and lateral cephalograms); and include no surgical or simultaneous treatment that could alter RME effects during the evaluation period. Articles without an adequate control group to factor out normal growth changes were excluded.Data extraction and synthesis Selected articles were independently evaluated by three researchers. Interexaminer discrepancies were resolved by discussion until a consensus was reached. A summary of sample size, retention period, measurement error and radiographs were listed in a table. A quality checklist of methods used was developed to evaluate the selected articles.Results The search identified 188 articles, of which three met the inclusion criteria. From the final three articles, one measured transverse changes, two anteroposterior changes, and two vertical changes. The only statistically significant difference in skeletal width increase for subjects before and after the peak pubertal growth spurt was lateronasal width (+1.5 mm). For the early-treated group, the maxillary width increase was significant (3 mm), but not for the late-treated group (0.9 mm). Regarding anteroposterior changes in the maxilla and mandible, no significant alterations were found. Short-term and long-term vertical skeletal changes associated with RME appeared to be restricted to the maxilla. The magnitude of change was small and had little, if any, clinical significance.Conclusions Long-term transverse skeletal maxillary increase is approximately 25% of the total dental expansion for prepubertal adolescents. Better long-term outcomes are expected in transverse changes because of RME in less skeletally mature patients. RME did not appear to produce clinically significant anteroposterior or vertical changes in the position of the maxilla and mandible. The conclusions from this systematic review should be considered with caution because only secondary-level evidence was found. Long-term randomised clinical trials (RCT) are needed.Evidence-Based Dentistry (2005) 6, 92. doi:10.1038/sj.ebd.6400359 [ABSTRACT FROM AUTHOR]