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Structure and ligand of a histone acetyltransferase bromodomain.
- Source :
- Nature; 6/3/1999, Vol. 399 Issue 6735, p491-496, 6p, 1 Color Photograph, 12 Diagrams
- Publication Year :
- 1999
-
Abstract
- Presents research which described the structure of the bromodomain of the histone-acetyltransferase (HAT) co-activator P/CAF. Role of histone acetylation in chromatin remodelling and gene activation; Details about bromodomains and their structure; Interaction of bromodomains with acetylated lysine; Recognition of acetyl-lysine by P/CAF; Function of the bromodomain in gene transcription regulation.
Details
- Language :
- English
- ISSN :
- 00280836
- Volume :
- 399
- Issue :
- 6735
- Database :
- Complementary Index
- Journal :
- Nature
- Publication Type :
- Academic Journal
- Accession number :
- 1909999
- Full Text :
- https://doi.org/10.1038/20974