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Epidemiological and clinical aspects of blackwater fever among African children suffering frequent malaria attacks

Authors :
Rogier, Christophe
Imbert, Patrick
Tall, Adama
Sokhna, Cheikh
Spiegel, André
Trape, Jean-François
Source :
Transactions of the Royal Society of Tropical Medicine & Hygiene; Mar2003, Vol. 97 Issue 2, p193-197, 5p
Publication Year :
2003

Abstract

Blackwater fever (BWF), one of the commonest causes of death of Europeans living in Africa at the beginning of the twentieth century, but rarely diagnosed since the 1950s, is related to Plasmodium falciparum malaria but there is considerable debate and controversy about its aetiology. From 1990 to 2000, the whole population of Dielmo, a village in Senegal, was involved in a prospective study of malaria. Three cases of BWF occurred in 3 children aged 4, 7 and 10 years, belonging to a subgroup of children who suffered malaria attacks every 4 to 6 weeks over many years, who had received repeated quinine treatment. The spread of chloroquine resistance, by increasing the use of more toxic alternative drugs, may expose endemic populations to a high incidence of severe side effects of antimalarials. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
00359203
Volume :
97
Issue :
2
Database :
Complementary Index
Journal :
Transactions of the Royal Society of Tropical Medicine & Hygiene
Publication Type :
Academic Journal
Accession number :
18934452
Full Text :
https://doi.org/10.1016/S0035-9203(03)90116-7