DELAYED NEURONAL AND GLIAL CHANGES IN SLA MODEL IN VITRO.

Authors :: Matyja, E.
Taraszewska, A.
Nagańska, E.
Rafałowska, J.
Grzywaczewska, E.
Source :: Folia Neuropathologica; 2005, Vol. 43 Issue 3, p215-215, 1/3p
Publication Year :: 2005
Abstract: This article presents an abstract of the research paper "Delayed Neuronal and Glial Changes in SLA Model In Vitro," which was discussed in the 13th Conference of the Polish Association of Neuropathologist. Chronic excitoxicity mediated through the defective glial and neuronal glutamate transport may contribute to several neurodegenerative diseases including amyotrophic lateral sclerosis. To determine the detailed ultrastructural characteristics of excitotoxic motor neuron neurodegeneration, the study used a model of slow excitotoxicity in vitro based on selective inhibition of glutamate uptake.