Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3,4,5)P3 suggest their interaction with protein binding partners.

Discusses research being done on pleckstrin-homology (PH) domains (3,4,5)-trisphosphate. Reference to a study by Peter Varnai and colleagues, published in a 2005 issue of the "Journal of Cell Science"; Description of green fluorescent proteins (GFP); Information on the pleckstrin-homology domains that are comprised by the GFP.