Magnetic biosensors for genetic screening of cystic fibrosis.

The article focuses on the use of magnetic bio-sensors for the genetic screening of cystic fibrosis. Different groups have worked on demonstrating the proposed magnetic biosensor concepts as a gene sensor, in which specific deoxyribonucleic acid (DNA) sequences are detected by the magneto-resistive sensors. Most groups pursued the static approach or post-hybridization detection approach, where known DNA sequences (probes) are first patterned onto the array of magnetic sensors. An aliquot of unknown DNA, called target or analyte, labeled with a bio-molecule called biotin is passed over the array, enabling hybridization if probe and target DNA sequences are complementary.