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A roadmap to precision medicine through post-genomic electronic medical records.

Authors :
Mendez, Kevin M.
Reinke, Stacey N.
Kelly, Rachel S.
Chen, Qingwen
Su, Mark
McGeachie, Michael
Weiss, Scott
Broadhurst, David I.
Lasky-Su, Jessica A.
Source :
Nature Communications; 2/17/2025, Vol. 16 Issue 1, p1-12, 12p
Publication Year :
2025

Abstract

The promise of integrating Electronic Medical Records (EMR) and genetic data for precision medicine has largely fallen short due to its omission of environmental context over time. Post-genomic data can bridge this gap by capturing the real-time dynamic relationship between underlying genetics and the environment. This perspective highlights the pivotal role of integrating EMR and post-genomics for personalized health, reflecting on lessons from past efforts, and outlining a roadmap of challenges and opportunities that must be addressed to realize the potential of precision medicine. The authors outline a framework uniting electronic medical records with post-genomic data to capture real-time physiological changes via periodic molecular snapshots, enabling a shift from reactive treatments to proactive, inclusive care. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20411723
Volume :
16
Issue :
1
Database :
Complementary Index
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
183072028
Full Text :
https://doi.org/10.1038/s41467-025-56442-4