Recent Research from Regional Center for Biotechnology Highlight Findings in Life Science (Placental Proteomics Reveals an Elevated Level of Aldo-keto Reductase 1-b1, Highlighting Its Potential Role In Spontaneous Preterm Birth).

Recent research from the Regional Center for Biotechnology in Faridabad, India, highlights the potential role of Aldo-keto Reductase 1-b1 (AKR1B1) in spontaneous preterm birth. The study conducted a nested case-control analysis of placental tissue samples, revealing 23 differentially expressed proteins, with AKR1B1 showing elevated levels in extreme preterm samples. The findings suggest that elevated AKR1B1 levels may play a significant role in preterm birth pathology by amplifying Prostaglandin-F2 alpha synthesis in the placenta. This research has been peer-reviewed and provides valuable insights into potential predictors of preterm birth. [Extracted from the article]